Dengue: Its Treatment with Pre & Probitocs

 Dengue: Why You Need to Know About It:

Dengue is no joke – it causes a “bone-breaking” illness and fever that basically wipes you out. The dengue fever virus is the most common virus that mosquitoes transmit and infects about 100 million people worldwide every year, killing about 25,000.


The WHO reports that over 2.5 billion people (that’s over 40% of the world’s population) are at risk for dengue (meaning, they live in an areas with dengue transmission), and an estimated 50-100 million infections occur worldwide each year.

Countries affected by Dengue

Let's Check how WHO defines Dengue

"Dengue is transmitted by the bite of a mosquito infected with one of the four dengue virus serotypes. It is a febrile illness that affects infants, young children and adults with symptoms appearing 3-14 days after the infective bite.

Dengue is not transmitted directly from person-to-person and symptoms range from mild fever, to incapacitating high fever, with severe headache, pain behind the eyes, muscle and joint pain, and rash. There is no vaccine or any specific medicine to treat dengue. People who have dengue fever should rest, drink plenty of fluids and reduce the fever using paracetamol or see a doctor.

Severe dengue (also known as dengue hemorrhagic fever) is characterized by fever, abdominal pain, persistent vomiting, bleeding and breathing difficulty and is a potentially lethal complication, affecting mainly children. Early clinical diagnosis and careful clinical management by trained physicians and nurses increase survival of patients."

Symptoms of dengue fever

A symptom is something the patient feels or reports, while a sign is something that other people, including the doctor detects. A headache may be an example of a symptom, while a rash may be an example of a sign.

As there are different severities of dengue fever, the symptoms can vary.

Mild dengue fever

Symptoms can appear up to seven days after the mosquito carrying the virus bites, and usually disappear after a week. This form of the disease hardly ever results in serious or fatal complications. The symptoms of mild dengue fever are:

• Aching muscles and joints
• Body rash that can disappear and then reappear
• High fever
• Intense headache
• Pain behind the eyes
• Vomiting and feeling nauseous.

Dengue hemorrhagic fever (DHF)

Symptoms during onset may be mild, but gradually worsen after a number of days. DHF can result in death if not treated in time. Mild dengue fever symptoms may occur in DHF, as well as the ones listed below:

• Bleeding from your mouth/gums

• Nosebleeds

• Clammy skin

• Considerably damaged lymph and blood vessels

• Internal bleeding, which can result in black vomit and feces (stools)

• Lower number of platelets in blood - these are the cells that help clot your blood

• Sensitive stomach

• Small blood spots under your skin

• Weak pulse.

Dengue shock syndrome

This is the worst form of dengue which can also result in death, again mild dengue fever symptoms may appear, but others likely to appear are:

• Intense stomach pain

• Disorientation

• Sudden hypotension (fast drop in blood pressure)

• Heavy bleeding

• Regular vomiting

• Blood vessels leaking fluid

• Death.

PROBIOTIC SUPPLEMENTATION, AS A TREATMENT IN DENGUE HEMORRHAGIC FEVER(DHF) I, II, III:

According to World Health Organization, dengue is the most rapidly spreading mosquito-borne viral disease in the world. In the last 50 years, the incidence has increased 30 fold with increasing geographic expansion to new countries. 

Man countries has done research on Probiotics against dengue and result was so encouraging! It can stop DHN in less than 24 hours!

In DHF probiotics supplementation was associated with:

• Higher proportion of dengue patient with resolution of fever, nose bleeding noted as early as 24th hour of treatment.
• Improvement of platelet count, hemoglobin and hematocrit was also noted.
• Hospital stay was shortened to 3.2 days.
• There was no significant effect on blood pressure, heart rate and respiratory rate.
• No adverse event with probiotic supplementation was observed. 

Vitamin B1 as a mosquito repellant:

Vitamin B1 (thiamine) is water soluble vitamin that contributes a lot in metabolic chemical  reactions  occurring  in  the  human  body.  If vitamin B1 is ingested more than body’s  requirements, excess  amount is  expelled  in urine  and from  skin  by perspiration.  The  way vitamin  B1  is removed  by the skin  provides  the  possibility  to  avert  mosquitoes. Particularly  if  commercially  available  mosquito repellents  are  not  available,  this  thiamine  could  be justified regardless of an attempt.

Colostrum as immune system booster:

Colostrum, the first milk coming out from a mother after delivery, has been well known to provide immunoglobulins, which are antibodies to help boost children’s immune system in combating various infections.

With the season of rains and floods around, dengue and other forms of respiratory and intestinal infections cannot be far behind. The administration of colostrum preparations from cows (bovine colostrum) may help in warding off infections associated with a depressed immune system.

Colostrum work as anti dengue: Colostrum aims to activate microphages directly. 

Role of microphages: (NK cells) engulfs & digest cancer cells, viruses & microbes.

Gut associated lymphoid tissue,is said to be the biggest macrophage pool in the body. Plenty of mircrophages exist in the peyer’s patch & colostrums aims to activate these microphages directly. Platelet-derived growth factor (PDGF).

Anti-dengue activity in human milk did not decrease over a  period of ten months after delivery.

Why B-Gut on Dengue Fever:

B-Gut is an ideal mixture of Pre & Probiotic{Fructo Oligosaccharide, Lactic Acid Bacillus, Streptococcus Faecallis , Clostridium Butyricum, Bacillus Mesenterico}, Vitamin B Variants, Colostrum, Methionine and Zinc Sulphate which is needed in defeating Dengue Fever. 

B-Gut not only helps you to overcome from Dengue Fever, it also prevents you from Diarrhea and loose motions. Many patients reports that they have pain in chest, loose motions post dengue recovery. It is due to anxiety. 

Preventing a Dengue Epidemic:

According to the CDC, the best means for preventing the spread of dengue involves “sustainable, community-based, integrated mosquito control, with limited reliance on chemical insecticides.” By eliminating as many sources of standing water as possible, you’ll be eliminating mosquito eggs and larvae.

Items that collect rainwater or are used to store water, such as plastic containers, drums, buckets, or used automobile tires, should be covered or properly discarded since they are mosquito breeding grounds. Animal water dishes, birdbaths, and flowerpots should be emptied and cleaned at least once a week.

                                      

In order to minimize your chances for mosquito bites, you can do the following:

• Make sure windows and doors are screened.
• Use bed nets when sleeping in a tropical zone
• Wear a safe mosquito repellent. Look for one with essential oils such as cinnamon oil, neem, and catnip, which are every bit are effective.
• When outdoors during times when mosquitoes are biting, wear long-sleeved shirts, hats and long pants tucked into socks.

Trust this blog enhances your knowledge and increase trust in our Products. We will keep update you new information, new articles about Health Awareness. 

Our Motto is  to keep World Healthy and we are well determined to it.

HAPPY READING..

- P.A.I.D, (Patient Awareness Initiative Department) Quest Biotech India Pvt. Ltd.

Gestational Diabetes Mellitus (GDM) To Be Conquered by L-Carnitine(Part-2)

Complications

Most women who have gestational diabetes deliver healthy babies. However, gestational diabetes that's not carefully managed can lead to uncontrolled blood sugar levels and cause problems for you and your baby, including an increased likelihood of needing a C-section to deliver.

Complications that may affect Baby

If you have gestational diabetes, your baby may be at increased risk of:

Excessive birth weight. Extra glucose in your bloodstream crosses the placenta, which triggers your baby's pancreas to make extra insulin. This can cause your baby to grow too large (macrosomia).

Early (preterm) birth and respiratory distress syndrome. A mother's high blood sugar may increase her risk of early labor and delivering her baby before its due date. Or her doctor may recommend early delivery because the baby is large.

Babies born early may experience respiratory distress syndrome — a condition that makes breathing difficult. Babies with this syndrome may need help breathing until their lungs mature and become stronger. Babies of mothers with gestational diabetes may experience respiratory distress syndrome even if they're not born early.

Low blood sugar (hypoglycemia). Sometimes babies of mothers with gestational diabetes develop low blood sugar (hypoglycemia) shortly after birth because their own insulin production is high. Severe episodes of hypoglycemia may provoke seizures in the baby.

Type 2 diabetes later in life. Babies of mothers who have gestational diabetes have a higher risk of developing obesity and type 2 diabetes later in life. Untreated gestational diabetes can result in a baby's death either before or shortly after birth.

Complications that may affect Mother:

Gestational diabetes may also increase the mother's risk of:

High blood pressure and preeclampsia. Gestational diabetes raises your risk of high blood pressure, as well as, preeclampsia — a serious complication of pregnancy that causes high blood pressure and other symptoms that can threaten the lives of both mother and baby.

Future diabetes. If you have gestational diabetes, you're more likely to get it again during a future pregnancy. You're also more likely to develop type 2 diabetes as you get older. However, making healthy lifestyle choices such as eating healthy foods and exercising can help reduce the risk of future type 2 diabetes.

Of those women with a history of gestational diabetes who reach their ideal body weight after delivery, fewer than 1 in 4 eventually develops type 2 diabetes.

Prevention

Beginning prenatal care early and having regular prenatal visits helps improve your health and the health of your baby. Having prenatal screening at 24 - 28 weeks into the pregnancy will help detect gestational diabetes early.

If you are overweight, decreasing your body mass index (BMI) to a normal range before you get pregnant will decrease your risk of developing gestational diabetes.

Treatment

The goals of treatment are to keep blood sugar (glucose) levels within normal limits during the pregnancy, and to make sure that the growing baby is healthy.

WATCHING YOUR BABY

• Your health care provider should closely check both you and your baby throughout the pregnancy. Fetal monitoring will check the size and health of the fetus.
• A nonstress test is a very simple, painless test for you and your baby.
• A machine that hears and displays your baby's heartbeat (electronic fetal monitor) is placed on your abdomen.
• Your health care provider can compare the pattern of your baby's heartbeat to movements and find out whether the baby is doing well.

DIET AND EXERCISE

• The best way to improve your diet is by eating a variety of healthy foods. You should learn how to read food labels, and check them when making food decisions. Talk to your doctor or dietitian if you are a vegetarian or on some other special diet.
• In general, when you have gestational diabetes your diet should:
• Be moderate in fat and protein
• Provide your carbohydrates through foods that include fruits, vegetables, and complex carbohydrates (such as bread, cereal, pasta, and rice)
• Be low in foods that contain a lot of sugar, such as soft drinks, fruit juices, and pastries
• If managing your diet does not control blood sugar (glucose) levels, you may be prescribed diabetes medicine by mouth or insulin therapy.
• Most women who develop gestational diabetes will not need diabetes medicines or insulin, but some will.

L-carnitine

L-carnitine is the biologically active form of the nonessential amino acid carnitine. Carnitine is produced in your body from the two amino acids methionine and lysine, and also is found in foods such as dairy products, meats and avocados. 

Supplementation with L-carnitine under medical supervision may benefit diabetic sufferers, although more research is needed to fully assess its efficacy.

L-carnitine and Gestational Diabetes Mellitus (GDM)

L-carnitine is involved in the transport of certain fatty acids into cells where they go through a process of oxidation. As a result of this process, energy is released. Supplementation with L-carnitine improves the usage of fat as a source of energy, lowers cholesterol and trygliceride levels and may reduce the risk of health problems in diabetics, who have impaired fat metabolism. L-carnitine has a protective effect on heart muscles and function, thus diabetics may benefit again from this supplement, as diabetes increases the risk of developing heart conditions. In clinical research, L-carnitine has been found to enhance the efficacy of conventional drugs in improving glucose and lipid levels in diabetics.

Scientists from the University of Vienna noted deficiency of carnitine in pregnant women from the 12th week of gestation through delivery leads to down-regulation of expression of certain enzymes involved in fatty acid metabolism; low mRNA levels of these enzymes promotes an increase in free fatty acid levels conducive to insulin resistance. The researchers found supplementation with L-carnitine tartrate increased relative mRNA levels of these enzymes in pregnant women.

In a release on the findings, researchers noted there appears to be increasing evidence that L-carnitine may play an important role during pregnancy, particularly in women following a meat-reduced or vegetarian diet.

CRT-E in Gestational Diabetes Mellitus (GDM)

Keep Up The Vigor

L Cartinine Supplementation to Prevent or Gestational diabetes mellitus(GDM):

“The results of the present study provide evidence that L-carnitine supplementation in pregnancy (2 g/day) avoids a striking increase in plasma FFA(free fatty acid), which are thought to be the main cause of insulin resistance and consequently gestational diabetes mellitus.”

Gynakol Geburtshilfliche Rundsch. 2009;49(4):230-5. doi: 10.1159/000301075. Epub 2010 May 19.

Trust this blog enhances your knowledge and increase trust in our Products. We will keep update you new information, new articles about Health Awareness. 

Our Motto is  to keep World Healthy and we are well determined to it.

HAPPY READING..

- P.A.I.D, (Patient Awareness Initiative Department) Quest Biotech India Pvt. Ltd.

Gestational Diabetes Mellitus (GDM) To Be Conquered by L-Carnitine(Part-1)

Gestational diabetes mellitus (GDM) affects between 2% and 5% of pregnant women. It is especially common during the last third of pregnancy. It affects 1% of those under the age of 20 and 13% of those over the age of 44. A number of ethnic groups including Asians, American Indians, Indigenous Australians, and Pacific Islanders are at higher risk. In 90% of people gestational diabetes will resolve after the baby is born. Women; however, are at an increased risk of developing type 2 diabetes. See the images:

Insulin is a hormone whose job is to enable glucose (sugar) in the bloodstream to enter the cells of the body, where sugar is the source of energy. All fetuses (babies) and placentas (afterbirths) produce hormones that make the mother resistant to her own insulin.

Most pregnant women produce more insulin to compensate and keep their blood sugar level normal. Some pregnant women cannot produce enough extra insulin and their blood sugar level rises, a condition called gestational diabetes. Gestational diabetes affects between 5 and 18 percent of women during pregnancy, and usually goes away after delivery.

What is Gestational diabetes mellitus (GDM)?

Gestational diabetes mellitus (GDM) is defined as glucose intolerance of various degrees that is first detected during pregnancy. GDM is detected through the screening of pregnant women for clinical risk factors and, among at-risk women, testing for abnormal glucose tolerance that is usually, but not invariably, mild and asymptomatic. 

GDM appears to result from the same broad spectrum of physiological and genetic abnormalities that characterize diabetes outside of pregnancy. Indeed, women with GDM are at high risk for having or developing diabetes when they are not pregnant.

Gestational diabetes mellitus (GDM) represents a heterogeneous group of metabolic disorders, which result in varying degrees of maternal hyperglycemia and pregnancy-associated risk. The frequency of GDM is rising globally and may also increase further as less-stringent criteria for the diagnosis are potentially adopted.

You may have a greater risk of developing gestational diabetes if you:

• Are obese when you become pregnant
• Have high blood pressure or other medical complications
• Have given birth to a large (greater than 9 pounds) baby before
• Have given birth to a baby that was stillborn or suffering from certain birth defects
• Have had gestational diabetes in previous pregnancies
• Have a family history of diabetes
• Come from certain ethnic backgrounds, including African, Hispanic, Asian, Native American, or Pacific Islander
• Are older than 30

But half of women who develop gestational diabetes have no risk factors.

What are the symptoms of gestational diabetes?

Gestational diabetes typically does not cause any noticeable signs or symptoms. This is why screening tests are so important. Rarely, an increased thirst or increased urinary frequency may be noticed.

Causes of gestational diabetes

Researchers don't know why some women develop gestational diabetes. To understand how gestational diabetes occurs, it can help to understand how pregnancy affects your body's glucose processing.

Your body digests the food you eat to produce sugar (glucose) that enters your bloodstream. In response, your pancreas — a large gland behind your stomach — produces insulin. Insulin is a hormone that helps glucose move from your bloodstream into your body's cells, where it's used as energy.

During pregnancy, the placenta, which connects your baby to your blood supply, produces high levels of various other hormones. Almost all of them impair the action of insulin in your cells, raising your blood sugar. Modest elevation of blood sugar after meals is normal during pregnancy.

As your baby grows, the placenta produces more and more insulin-blocking hormones. In gestational diabetes, the placental hormones provoke a rise in blood sugar to a level that can affect the growth and welfare of your baby. Gestational diabetes usually develops during the last half of pregnancy — sometimes as early as the 20th week, but generally not until later.

Exams and Tests

Gestational diabetes usually starts halfway through the pregnancy. All pregnant women should receive an oral glucose tolerance test between the 24th and 28th week of pregnancy to screen for the condition. Women who have risk factors for gestational diabetes may have this test earlier in the pregnancy.

Once you are diagnosed with gestational diabetes, you can see how well you are doing by testing your glucose level at home. The most common way involves pricking your finger and putting a drop of your blood on a machine that will give you a glucose reading.


To know more about Complications of GDM and its effect on Baby & Mother, and how to conquer GDM by L-Carnitine read second part of this Blog.

Trust this blog enhances your knowledge and increase trust in our Products. We will keep update you new information, new articles about Health Awareness. 

Our Motto is  to keep World Healthy and we are well determined to it.

HAPPY READING..

- P.A.I.D, (Patient Awareness Initiative Department) Quest Biotech India Pvt. Ltd.

All About INFERTILITY

Female infertility refers to infertility in female humans. It affects an estimated 48 million women with the highest prevalence of infertility affecting people in South Asia, Sub-Saharan Africa, North Africa/Middle East, and Central/Eastern Europe and Central Asia. Infertility is caused by many sources, including nutrition, diseases, and other malformations of the uterus. Infertility affects women from around the world, and the cultural and social stigma surrounding it varies.

What is exactly Infertility?

NICE guidelines state that: "A woman of reproductive age who has not conceived after 1 year of unprotected vaginal sexual intercourse, in the absence of any known cause of infertility, should be offered further clinical assessment and investigation along with her partner."

A clinical definition of infertility by the WHO and ICMART is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.” 

To become pregnant, each of these factors is essential:

• You need to ovulate. Achieving pregnancy requires that your ovaries produce and release an egg, a process known as ovulation. Your doctor can help evaluate your menstrual cycles and confirm ovulation.
• Your partner needs sperm. For most couples, this isn't a problem unless your partner has a history of illness or surgery. Your doctor can run some simple tests to evaluate the health of your partner's sperm.
• You need to have regular intercourse. You need to have regular sexual intercourse during your fertile time. Your doctor can help you better understand when you're most fertile during your cycle.
• You need to have open fallopian tubes and a normal uterus. The egg and sperm meet in the fallopian tubes, and the pregnancy needs a healthy place to grow.

For pregnancy to occur, every part of the complex human reproduction process has to take place just right. The steps in this process are as follows:

• One of the two ovaries releases a mature egg.
• The egg is picked up by the fallopian tube.
• Sperm swim up the cervix, through the uterus and into the fallopian tube to reach the egg for fertilization.
• The fertilized egg travels down the fallopian tube to the uterus.
• The fertilized egg implants and grows in the uterus.
• In women, a number of factors can disrupt this process at any step. Female infertility is caused by one or more of these factors.

What Causes Female Infertility?

There are a number of things that may be keeping you from getting pregnant:

Damage to your fallopian tubes. These structures carry eggs from your ovaries, which produce eggs, to the uterus, where the baby develops. They can get damaged when scars form after pelvic infections, endometriosis, and pelvic surgery. That can prevent sperm from reaching an egg.

Hormonal problems. You may not be getting pregnant because your body isn't going through the usual hormone changes that lead to the release of an egg from the ovary and the thickening of the lining of the uterus.

Cervical issues. Some women have a condition that prevents sperm from passing through the cervical canal.

Uterine trouble. You may have polyps and fibroids that interfere with getting pregnant. Uterine polyps and fibroids happen when too many cells grow in the endometrium, the lining of the uterus.

"Unexplained" infertility. For about 20% of couples who have infertility problems, the exact causes are never pinpointed.

Tests for Infertility:

Your doctor may order several tests, including a blood test to check hormone levels and an endometrial biopsy to examine the lining of your uterus.

Hysterosalpingography (HSG). This procedure involves ultrasound or X-rays of your reproductive organs. A doctor injects either dye or saline and air into your cervix, which travel up through your fallopian tubes. With this method, your doctor can check to see if the tubes are blocked.

Laparoscopy. Your doctor puts a laparoscope -- a slender tube fitted with a tiny camera -- through a small cut near your belly button. This lets him view the outside of your uterus, ovaries, and fallopian tubes to check for abnormal growths. The doctor can also see if your fallopian tubes are blocked.

How Is Female Infertility Treated?

Laparoscopy. If you've been diagnosed with tubal or pelvic disease, one option is to get surgery to reconstruct your reproductive organs. Your doctor puts a laparoscope through a cut near your belly button to get rid of scar tissue, treat endometriosis, open blocked tubes, or remove ovarian cysts, which are fluid-filled sacs that can form in the ovaries.

Womfil as a Treatment for Infertility:

According to various study, i,e. Sildenafil Citrate, our Brand name is Womfil has been shown to be useful in increasing endometrial thickness and achieving pregnancy in women with varied uterine disorders.

Womfil is an effective and EFFERVESCENT Tablet which will Empower Women, and nurtures Life. 

Trust this blog enhances your knowledge and increase trust in our Products. We will keep update you new information, new articles about Health Awareness. 

Our Motto is  to keep World Healthy and we are well determined to it.

HAPPY READING..

- P.A.I.D, (Patient Awareness Initiative Department) Quest Biotech India Pvt. Ltd.