Antibiotics, also known as antibacterials and antimicrobials, revolutionized medicine during the later half of the 20th century. But as time goes on, the success of antibiotics may be completely cancelled out by their combative counterparts: resistant bacteria.
Humans have overused antibiotics simply by harnessing them to treat all sorts of infections from pneumonia to strep throat — but also by sometimes taking too much of them, or infusing them into agricultural systems, animals, and food products , as the CDC illustrates . This overuse has opened the door for bacteria to evolve into resistant strains to beat out drugs. We’re now in a place where changes desperately need to be made in order to prevent millions of deaths from antibiotic resistance in the coming decades. These microscopic microbes seem to be smarter than us.
The Discovery of Antibiotics:
1928. Alexander Fleming, a Scottish biologist, took the fight against infections to a new level when he identified penicillin, making this the year that the modern antibiotic era began.
The discovery had apparently been an accident. Fleming had left an uncovered Petri dish of Staphylococcus bacteria near an open window in his basement lab, and in the morning found that mold growth had inhibited the bacteria. Penicillin, which comes from a type of fungi known as Penicillin rubens , became the first compound to be used officially as an antibiotic.
How Do Antibiotics Work?
Various types of antibiotics work in either of the following two ways:
A Bactericidal antibiotic kills the bacteria generally by either interfering with the formation of the bacterium's cell wall or its cell contents.
Penicillin, daptomycin, fluoroquinolones, metronidazole, nitrofurantoin and co-trimoxazole are some example of Bactericidal antibiotics.
A Bacteriostatic antibiotic stops bacteria from multiplying by interfering with bacterial protein production, DNA replication, or other aspects of bacterial cellular metabolism.
Some Bacteriostatic antibiotics are tetracyclines, sulphonamides, spectinomycin, trimethoprim, chloramphenicol, macrolides and lincosamides.
Problems With Antibiotics
The success of antibiotics has been impressive. At the same time, however, excitement about them has been tempered by a phenomenon called antibiotic resistance. This is a problem that surfaced not long after the introduction of penicillin and now threatens the usefulness of these important medicines.
Almost from the beginning, doctors noted that in some cases, penicillin was not useful against certain strains of Staphylococcus aureus (bacteria that causes skin infections). Since then, this problem of resistance has grown worse, involving other bacteria and antibiotics. This is a public health concern. Increasingly, some serious infections have become more difficult to treat, forcing doctors to prescribe a second or even third antibiotic when the first treatment does not work.
In light of this growing antibiotic resistance, many doctors have become much more careful in the way they prescribe these medicines. They see the importance of giving antibiotics only when they’re absolutely necessary.
In fact, one recent survey of office-based physicians, published in JAMA: The Journal of the American Medical Association in 2002, showed that doctors lowered the number of antibiotic prescriptions they prescribed for children with common respiratory infections by about 70% during the 2010s.
Serious diseases that once killed thousands of youngsters each year have been almost eliminated in many parts of the world because of the widespread use of childhood vaccinations.
In much the same way, the discovery of Antimicrobial drugs (antibiotics) was one of the most significant medical achievements of the 20th century. There are several types of antimicrobials—antibacterials, antivirals, antifungals, and antiparasitic drugs. Of course, antimicrobials aren’t magic bullets that can heal every disease. When used at the right time, they can cure many serious and life-threatening illnesses.
Humans have overused antibiotics simply by harnessing them to treat all sorts of infections from pneumonia to strep throat — but also by sometimes taking too much of them, or infusing them into agricultural systems, animals, and food products , as the CDC illustrates . This overuse has opened the door for bacteria to evolve into resistant strains to beat out drugs. We’re now in a place where changes desperately need to be made in order to prevent millions of deaths from antibiotic resistance in the coming decades. These microscopic microbes seem to be smarter than us.
The Discovery of Antibiotics:
"One sometimes finds what one is not looking for"
1928. Alexander Fleming, a Scottish biologist, took the fight against infections to a new level when he identified penicillin, making this the year that the modern antibiotic era began.
The discovery had apparently been an accident. Fleming had left an uncovered Petri dish of Staphylococcus bacteria near an open window in his basement lab, and in the morning found that mold growth had inhibited the bacteria. Penicillin, which comes from a type of fungi known as Penicillin rubens , became the first compound to be used officially as an antibiotic.
How Do Antibiotics Work?
Various types of antibiotics work in either of the following two ways:
A Bactericidal antibiotic kills the bacteria generally by either interfering with the formation of the bacterium's cell wall or its cell contents.
Penicillin, daptomycin, fluoroquinolones, metronidazole, nitrofurantoin and co-trimoxazole are some example of Bactericidal antibiotics.
A Bacteriostatic antibiotic stops bacteria from multiplying by interfering with bacterial protein production, DNA replication, or other aspects of bacterial cellular metabolism.
Some Bacteriostatic antibiotics are tetracyclines, sulphonamides, spectinomycin, trimethoprim, chloramphenicol, macrolides and lincosamides.
Problems With Antibiotics
The success of antibiotics has been impressive. At the same time, however, excitement about them has been tempered by a phenomenon called antibiotic resistance. This is a problem that surfaced not long after the introduction of penicillin and now threatens the usefulness of these important medicines.
Almost from the beginning, doctors noted that in some cases, penicillin was not useful against certain strains of Staphylococcus aureus (bacteria that causes skin infections). Since then, this problem of resistance has grown worse, involving other bacteria and antibiotics. This is a public health concern. Increasingly, some serious infections have become more difficult to treat, forcing doctors to prescribe a second or even third antibiotic when the first treatment does not work.
In light of this growing antibiotic resistance, many doctors have become much more careful in the way they prescribe these medicines. They see the importance of giving antibiotics only when they’re absolutely necessary.
In fact, one recent survey of office-based physicians, published in JAMA: The Journal of the American Medical Association in 2002, showed that doctors lowered the number of antibiotic prescriptions they prescribed for children with common respiratory infections by about 70% during the 2010s.
A Look Back
Serious diseases that once killed thousands of youngsters each year have been almost eliminated in many parts of the world because of the widespread use of childhood vaccinations.
In much the same way, the discovery of Antimicrobial drugs (antibiotics) was one of the most significant medical achievements of the 20th century. There are several types of antimicrobials—antibacterials, antivirals, antifungals, and antiparasitic drugs. Of course, antimicrobials aren’t magic bullets that can heal every disease. When used at the right time, they can cure many serious and life-threatening illnesses.
Cefqst-O - Empirical Management
Cefixime 200 mg, Ofloxacin 200 mg, Along with
Lactic Acid Bacillus 2.5 Billion Spores
Trust and Infallibility: Major Concern When Rx Antibiotics
•WHO recommended first line therapy.(IJBAMR-SEP2012,VOL1
I-4,P296-303)
•Gut friendly Antimicrobial agent with Symbiotic bactericidal
action.
•Pharmokinetically compatible with dual mode of action
•Effective against ESBL with Rapid bacteriological
eradication.
•Prevent the growth of Putrefactive microorganism.
•Produce environment which are Non- Codusive to
the growth of pathogens.
•76.5% of patients reported Empirical Management of infection
with excellent efficacy, tolerability & safety(American Journal of
Advances in Medical Sciences-2013,vol-1,No-2)
“Cefqst-O Works
Instantly And Synergistically And Gives Better Patient Compliance.”
Indications:
- Dental Infection
- URT/LRT Infection
- Typhoid/MDR Typhoid
- UTI/Gynecological Infection
- Surgical Prophylaxis & After Surgery
- ENT Infection
- Pyerxia of Unknown Origin
- Skin & Soft Tissue Infection
- Intra Abdominal Infection
Cefqst-O is Associating your Trust & Infallibility with EBM(Emperical Bacteriocidal Management)
Trust this blog enhances your knowledge and increase trust in our Products. We will keep update you new information, new articles about Health Awareness.
Our Motto is to keep World Healthy and we are well determined to it.
HAPPY READING..
- P.A.I.D, (Patient Awareness Initiative Department) Quest Biotech India Pvt. Ltd.
